8/24/2021 Prior to 4:00 p.m., New York time, clubs must reduce rosters to a maximum of 80 players on the Active/Inactive List.
8/26/2021 TO 8/29/2021 Third Preseason Weekend.
8/31/2021 Prior to 4:00 p.m., New York time, clubs must reduce rosters to a maximum of 53 players on the Active/Inactive List.
8/31/2021 Simultaneously with the roster reduction to 53 players, clubs that have players in the categories of Active/Physically Unable to Perform or Active/Non-Football Injury or Illness must select one of the following options: place player on Reserve/Physically
9/1/2021 Claiming period for players placed on waivers at the final roster reduction will expire at 4:00 p.m., New York time.
9/1/2021 Upon receipt of the Personnel Notice, clubs may establish a Practice Squad, subject to the applicable limits negotiated for the 2021 season (clubs participating in the International Player Development Program may sign one additional international player
9/1/2021 Beginning at 4:00 p.m., New York time, any player placed on Reserve/Injured or Reserve/Non-Football Injury or Illness during the regular season or postseason, may be designated for return later in the season, subject to the applicable procedures negotiate
9/5/2021 Final day of preseason training camp for all clubs, as defined in CBA Article 23, Section 10
9/6/2021 TO 9/11/2021 In accordance with the Personnel (Injury) Report Policy, each club is required to file a Practice Report with the NFL Communications department by 4:00 p.m., New York time, (or as soon as possible after the completion of practice) every Wednesday, Thursday